Genome-wide analysis of DNA methylation in buccal cells: a study of monozygotic twins and mQTLs
| Title | Genome-wide analysis of DNA methylation in buccal cells: a study of monozygotic twins and mQTLs |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | van Dongen, J, Ehli, EA, Jansen, R, van Beijsterveldt, CEM, Willemsen, G, Hottenga, JJ, Kallsen, NA, Peyton, SA, Breeze, CE, Kluft, C, Heijmans, BT, Bartels, M, Davies, GE, Boomsma, DI |
| Journal | Epigenetics {&} Chromatin |
| Volume | 11 |
| Pagination | 54 |
| Date Published | Sep |
| ISSN | 1756-8935 |
| Abstract | DNA methylation arrays are widely used in epigenome-wide association studies and methylation quantitative trait locus (mQTL) studies. Here, we performed the first genome-wide analysis of monozygotic (MZ) twin correlations and mQTLs on data obtained with the Illumina MethylationEPIC BeadChip (EPIC array) and compared the performance of the EPIC array to the Illumina HumanMethylation450 BeadChip (HM450 array) for buccal-derived DNA. |
| URL | https://doi.org/10.1186/s13072-018-0225-x |
| DOI | 10.1186/s13072-018-0225-x |
