Genome-Wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits

TitleGenome-Wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits
Publication TypeJournal Article
Year of Publication2024
AuthorsVerhoef, E, Allegrini, AG, Jansen, PR, Lange, K, Wang, CA, Morgan, AT, Ahluwalia, TS, Symeonides, C, Andreassen, OA, Bartels, M, Boomsma, D, Dale, PS, Ehli, E, Fernandez-Orth, D, Guxens, M, Hakulinen, C, Harris, KMullan, Haworth, S, de Hoyos, L, Jaddoe, V, Keltikangas-Järvinen, L, Lehtimäki, T, Middeldorp, C, Min, JL, Mishra, PP, Njølstad, PRasmus, Sunyer, J, Tate, AE, Timpson, N, van der Laan, C, Vrijheid, M, Vuoksimaa, E, Whipp, A, Ystrom, E, Consortium, ACTION, group, BInfant Stu, Eising, E, Franken, M-C, Hypponen, E, Mansell, T, Olislagers, M, Omerovic, E, Rimfeld, K, Schlag, F, Selzam, S, Shapland, CYang, Tiemeier, H, Whitehouse, AJO, Saffery, R, Bønnelykke, K, Reilly, S, Pennell, CE, Wake, M, Cecil, CAM, Plomin, R, Fisher, SE, Pourcain, BSt.
JournalBiological Psychiatry
Volume95
Issue9
Pagination859 - 869
Date Published2024/05/01
ISBN Number0006-3223
Abstract

BackgroundThe number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta?genome-wide association study of vocabulary acquisition and investigated polygenic overlap with literacy, cognition, developmental phenotypes, and neurodevelopmental conditions, including attention-deficit/hyperactivity disorder (ADHD).BackgroundThe number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta?genome-wide association study of vocabulary acquisition and investigated polygenic overlap with literacy, cognition, developmental phenotypes, and neurodevelopmental conditions, including attention-deficit/hyperactivity disorder (ADHD).

DOI10.1016/j.biopsych.2023.11.025